Physiological constipation Written by Dr Harold Gunatillake – Health writer Moments of irregular constipation causing blockage are common among healthy people at one time or another and is not considered serious. When constipation becomes regular, more persistent and progressive, then one has to take serious note of and get investigated. Endoscopy and barium studies including blood tests are done preliminarily to find out whether some pathological event is happening within the gut. Sometimes, you may visit the toilet and have a very hard motion like little hard balls and needs to strain a lot to evacuate. This situation by definition is also considered as constipation, requiring attention. ...